tert-Butyl (trans-4-aminomethylcyclohexyl)carbamate

tert-Butyl (trans-4-aminomethylcyclohexyl)carbamate - Names and Identifiers

Name	tert-Butyl (trans-4-aminomethylcyclohexyl)carbamate
Synonyms	trans-4-(boc-amino)cyclohexylmethylamine tert-Butyl(trans-4-aomethylcyclohexyl)carbamate tert-butyl N-[4-(aminomethyl)cyclohexyl]carbamate TERT-BUTYL TRANS-4-AMINOMETHYLCYCLOHEXYLCARBAMATE TERT-BUTYLTRANS-L-4-AMINOMETHYLCYCLOHEXYCARBAMATE tert-Butyl (trans-4-aminomethylcyclohexyl)carbamate TERT-BUTYL TRANS-L-4-AMINOMETHYL CYCLOHEXYL CARBAMATE carbamic acid [4-(aminomethyl)-2-tert-butylcyclohexyl] ester CarbaMic acid,N-[trans-4-(aMinoMethyl)cyclohexyl]-, 1,1-diMethylethyl ester
CAS	177583-27-6
InChI	InChI=1/C12H24N2O2/c1-12(2,3)16-11(15)14-10-6-4-9(8-13)5-7-10/h9-10H,4-8,13H2,1-3H3,(H,14,15)/t9-,10-

tert-Butyl (trans-4-aminomethylcyclohexyl)carbamate - Physico-chemical Properties

Molecular Formula	C12H24N2O2
Molar Mass	228.33
Density	1.01±0.1 g/cm3(Predicted)
Boling Point	342.4±11.0 °C(Predicted)
Flash Point	160.9°C
Water Solubility	Slightly soluble in water.
Vapor Presure	7.54E-05mmHg at 25°C
pKa	12.52±0.40(Predicted)
Storage Condition	under inert gas (nitrogen or Argon) at 2–8 °C
Refractive Index	1.487

tert-Butyl (trans-4-aminomethylcyclohexyl)carbamate - Introduction

tert-Butyl (trans-4-aminomethylcyclohexyl)carbamate, chemical formula C12H23NO2, is an organic compound. The following is a description of its nature, use, formulation and safety information:

Nature:
tert-Butyl (trans-4-aminomethylcyclohexyl)carbamate is a colorless to pale yellow liquid with a faint special odor. It has a density of 0.979g/cm³, a melting point of -25 ° C, and a boiling point of 233 ° C. It is insoluble in water but soluble in organic solvents such as ethanol and dimethylformamide.

Use:
tert-Butyl (trans-4-aminomethylcyclohexyl)carbamate is an important chemical intermediate. It is mainly used in organic synthesis reactions, such as synthetic drugs and pesticides. It is also used as a directional synthesis initiator and additive.

Method:
The preparation method of tert-Butyl (trans-4-aminomethylcyclohexyl)carbamate is specifically as follows: First, tert-butyl carbamate and p-toluenesulfonate are reacted in an appropriate solvent to obtain tert-butyl p-toluenesulfonate. This salt is then reacted with cyclohexylamine, 3-ethanolamine and the like as reagents to produce the desired product.

Safety Information:
tert-Butyl (trans-4-aminomethylcyclohexyl)carbamate is generally stable under normal use and storage conditions. However, it can be irritating to the skin and eyes and has effects on the respiratory and digestive systems. Therefore, direct contact with skin, eyes and mouth should be avoided during use. At the same time, it is necessary to operate in a well-ventilated area and use personal protective equipment, such as laboratory gloves, safety glasses and protective equipment. In case of accidental exposure or ingestion, contact your doctor immediately for help.

Last Update：2024-04-09 21:11:58